Mitotic indices of human bone marrow cells. II. The use of mitotic indices for estimation of time parameters of proliferation in serially connected multiplicative cellular compartments.
نویسندگان
چکیده
By SVEN-AGE KILLMANN, EUGENE P. CRONKITE, T. M. FLIEDNER, VIcroR P. BOND AND GEORGE BRECHER T HE PURPOSE of this paper is to define the information that is needed in order to use mitotic indices for computation of time parameters of catenated cytologic compartments such as exist in hemopoiesis. The considerations are also applicable to cell renewal systems in general. A list of symbols and definitions used is presented in table 1. By definition, the mitotic index is the fraction of a cell population in mitosis:
منابع مشابه
Mitotic indices of human bone marrow cells. I. Number and cytologic distribution of mitoses.
By SVEN-AGE KILLMANN, EUGENE P. CRONKITE, T. M. FLIEDNER AND VIc’roR P. BOND T HE OBJECTIVES of the present papers are threefold: In part I, data on the mitotic indices of specific cell types ( specific mitotic index ) in normal human bone marrow will be presented. In part II, restrictions in the use of mitotic index for computation of cytologic time parameters which have not been appreciated i...
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عنوان ژورنال:
- Blood
دوره 21 شماره
صفحات -
تاریخ انتشار 1963